Tottenham Hotspur face the toughest test of their campaign so far on Saturday evening, when they make the long trip up north to face the champions Manchester City, but they will be without four men for the clash, according to their official website.
Spurs will be looking to get a lot closer to the Citizens over the course of the Premier League this term, and they could make big inroads into the gap they need to close, if they come out on top at the Etihad Stadium.
Tottenham are expected to be up against it, when they face a City side, who are not just continuing the defence of their title, but who go into the clash off the back of a 5-0 win on the opening day of the season.
Spurs themselves got off the mark on the first day of action, when they saw off the challenge of Aston Villa and if they can come out on top at the Etihad, they will lay a real marker down for the months ahead.
However in order to do that, Tottenham are going to have to find a way to win without four star players, who will be missing the contest for various reasons.
Spurs will be without the injured trio of Dele Alli, Juan Foyth and Ryan Sessegnon, while leading attacker Son Heung-Min is suspended for the match and could be a big loss as a result.
In more positive news for Tottenham, left-back Ben Davies has returned to training and could well feature in Manchester.
These two sides played out some epic encounters last season, none less than that amazing Champions League quarter final, which had just about everything in it.
Spurs came out on top over the two legs in that tie, something that they will hope will give them the belief to stun the Citizens on their own patch, and announce themselves as genuine title contenders.