Southampton are due to play against Manchester City in a League Cup round of 16 clash at the Etihad Stadium on Tuesday night.
The Citizens are expected to ring in changes as they prioritise the Premier League.
Southampton will go into the clash as underdogs but should nevertheless fancy their chances of getting a positive result from the game.
The Saints must look to play a competitive brand of football against the reigning champions in order to regain some confidence following their 9-0 demolition at the hands of Leicester City last Friday.
Southampton manager Ralph Hasenhuttl can perhaps use the game as a means of experimenting with different players and formations.
If the south coast club ends up losing, it will not be the end of the world.
The Saints do not have any serious injury problems to worry about.
Southampton will be without key defender Ryan Bertrand for the City clash as he is suspended following a red card against Leicester, according to Sky Sports.
The report also names Cedric Soares and Moussa Djenepo as unavailable for the game in Manchester.
Southampton boss Hasenhuttl will surely make a number of changes to the team that capitulated on Friday night.
Many of the Southampton players who started the mauling at the hands of Leicester will be demotivated and could be dropped.
City’s defence has been their weak point this season. If Norwich City could exploit Pep Guardiola’s charges in the League, than it is also likely that the South Coast club will be able to do so.
Southampton fans will hope their side can replicate the performances of Norwich City and Wolves in springing a surprise result against Guardiola’s men.