Crystal Palace’s injury crisis has gone from bad to worse with full-back Patrick van Aanholt sustaining a hamstring injury in the 2-1 victory over West Ham on Boxing Day.
Striker Christian Benteke is also sidelined for the next few weeks with a muscle problem, according to Palace manager Roy Hodgson.
Palace are already without Jeffrey Schlupp, Gary Cahill, Joel Ward, Scott Dann and Andros Townsend, as they prepare to face Southampton on Saturday.
The Eagles travel to an in-form Saints outfit with all of these seven players ruled out, while Cheikhou Kouyate claimed he has a groin problem but will make himself available for selection.
The injury concerns leave Palace boss Hodgson extremely short of options amidst the busy festive period and it would not be a surprise to see the veteran manager ask the Selhurst Park board for new signings in January.
A late Jordan Ayew winner against West Ham propelled Palace to ninth place in the Premier League standings, eight points above the relegation zone with half the season over.
Southampton beat Chelsea away last time out, making it four wins in their last six matches and climbing to 14th place.
Southampton enjoy a good record against the Eagles and beat them 2-0 last year in the same fixture.